hardware and recent drivers with OpenGL 3 support are required for some modules
OpenGL modules may be disabled - if hardware was not detected or optionally
Warning: there are some possible issues with Linux open source Radeon drive: older version can crash, if texture size exceeds resources and automatic down-sampling of texture can fail; very big ROIs or very many images may exceed limit of 65536 VBOs. Proprietary drivers don't have the issues. Anyway in most cases open source Radeon driver will work.
RAM
min. 1 GB, recommended 8 GB, better 16 GB and more